| 英文名稱 | Anti-TERT Polyclonal Antibody |
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| 宿主 | Rabbit |
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| 別名 | EST2;TCS1;TRT;HEST2;TP2 |
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| 應用 | IHC |
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| 稀釋比例 | IHC 1:50-200. |
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| 交叉反應 | Mouse |
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| 蛋白分子量 | 127kDa |
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| Gene ID | 7015 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
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| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | A synthetic peptide of human TERT |
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| 性狀 | 液體 |
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| Public Immunogen Range | A synthetic peptide of human TERT |
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| Subcellular Locations | Cytoplasm |
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| Swiss Prot | O14746 |
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| 克隆類型 | Polyclonal Antibody |
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| 背景資料 | Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. |
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