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當前位置:> 供求商機> 190101—磁性固定化金屬親和層析填料

[供應]190101—磁性固定化金屬親和層析填料

貨物所在地:北京北京市

更新時間:2024-03-08 09:14:03

有效期:2024年3月8日 -- 2025年3月9日

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Immobilised metal affinity chromatography (IMAC) has been widely employed as a powerful separation approach in the purification of a broad range of proteins and peptides.

Product IntroductionImmobilised metal affinity chromatography (IMAC) has been widely employed as a powerful separation approach in the purification of a broad range of proteins and peptides. It is based on the specific interactions between certain transitional metal ions, mostly Cu2+, Ni2+, Zn2+ and Co2+ to the exposed amino acid surface chains containing histidine (or cysteine and tryptophane). The presence of several adjacent histidines such as (His)6-tag increases the affinity to immobilised metal ions. Increasingly, IMAC resins are employed for the purification of histidine-tagged recombinant proteins expressed in bacteria, yeast and mammalian cells. There are other applications of IMAC resins to purification of certain native non-tagged proteins as well, such as interferons, lectins, antibodies, serum and plasma proteins, peptides and peptide hormones.

Product Properties:

Four types of IMAC SepFast MAG are supplied in 5 ml format with precharged metal ions as Ni SepFast MAG, Cu SepFast MAG, Zn SepFast MAG and Co SepFast MAG. A special pack that contains the above four pre-charged resins (1 ml each type) is supplied as well for the screening purpose.


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