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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Storage

-20°C/1 year

Specificity

CAN3 Polyclonal Antibody detects endogenous levels of protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from part region of human protein

Uniprot No

P20807

Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

calpain 3(CAPN3) Homo sapiens Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008],

Other

CAPN3 CANP3 CANPL3 NCL1, Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)

Concentration

1 mg/ml