您好, 歡迎來到化工儀器網(wǎng)! 登錄| 免費(fèi)注冊(cè)| 產(chǎn)品展廳| 收藏商鋪|
提供商
靶點(diǎn)科技(北京)有限公司資料大小
206KB資料圖片
下載次數(shù)
17次資料類型
PDF 文件瀏覽次數(shù)
183次Kerafast ENH001 Anti-DNA-RNA Hybrid [S9.6] Antibody 針對(duì)ΦX174噬菌體衍生的合成DNA-RNA抗原產(chǎn)生該小鼠單克隆抗體,并識(shí)別各種長(zhǎng)度的RNA-DNA雜交體。
產(chǎn)品特色:
對(duì)DNA-RNA雜交體具有高度特異性和親和力
可用于檢測(cè)R環(huán)
不與單鏈DNA或雙鏈DNA交叉反應(yīng)
對(duì)于富含AU的雙鏈RNA,已觀察到輕微的交叉反應(yīng)(約5倍)。
對(duì)于長(zhǎng)度為8,10,15和23個(gè)堿基對(duì)的雜交體顯示出高親和力結(jié)合
DNA-RNA雜合體是真核細(xì)胞中的天然存在,這些za種的水平在具有高轉(zhuǎn)錄活性的位點(diǎn)增加,例如在轉(zhuǎn)錄起始,抑制和延伸期間。由于RNA-DNA雜交體影響基因組不穩(wěn)定性,S9.6抗體是一種有用的試劑,可幫助研究這些za種在DNA復(fù)制或其他細(xì)胞過程中形成的R環(huán)和損傷的后果。此外,S9.6抗體可有效識(shí)別用于微陣列研究的RNA-DNA雜交。
背景介紹:
DNA-RNA hybrids are a natural occurrence within eukaryotic cells, with levels of these hybrids increasing at sites with high transcriptional activity, such as during transcription initiation, repression, and elongation. Because RNA-DNA hybrids influence genomic instability, the S9.6 antibody is a useful reagent to help study the consequences of R-loops and lesions formed by these hybrids during DNA replication or other cellular processes. In addition, the S9.6 antibody is effective in recognizing RNA-DNA hybridization for microarray studies。
產(chǎn)品詳情:
Product Type: | Antibody |
Name: | Anti-DNA-RNA Hybrid [S9.6] |
Antigen: | S9.6 ΦX174 bacteriophage-derived synthetic DNA–RNA antigen |
Isotype: | Rabbit IgG |
Fusion Tag(s): | Mouse Fab version contains His-tag |
Clone Name: | S9.6 |
Reactivity: | High specificity and affinity for DNA/RNA hybrids and other A-form nucleic acid hybrids |
Immunogen: | ΦX174 bacteriophage-derived synthetic DNA/RNA |
Purification Method: | Protein A/G |
Buffer: | ENHOO1: PBS, 0.05% (w/v) Sodium Azide Ab01137- : PBS with 0.02% Proclin 300 |
Tested Applications: | Dot Blot Analysis: 0.2 µg/mL. |
請(qǐng)輸入賬號(hào)
請(qǐng)輸入密碼
請(qǐng)輸驗(yàn)證碼
以上信息由企業(yè)自行提供,信息內(nèi)容的真實(shí)性、準(zhǔn)確性和合法性由相關(guān)企業(yè)負(fù)責(zé),化工儀器網(wǎng)對(duì)此不承擔(dān)任何保證責(zé)任。
溫馨提示:為規(guī)避購(gòu)買風(fēng)險(xiǎn),建議您在購(gòu)買產(chǎn)品前務(wù)必確認(rèn)供應(yīng)商資質(zhì)及產(chǎn)品質(zhì)量。