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TA-01

CAS No. : 1784751-18-3

產品活性：TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC₅₀s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 acts as a cardiogenic inhibitor.

研究領域：Cell Cycle/DNA Damage  |  Stem Cell/Wnt  |  MAPK/ERK Pathway  |  Autophagy

作用靶點：Casein Kinase  |  p38 MAPK  |  Autophagy

In Vitro: TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC₅₀s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 (5 μM) is not cytotoxic, completely inhibits cardiogenesis, but induces cardiogenesis at lower concentration.

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