保存條件：-80°C(dryice)保質期：3-18month英文名：AAV9Luciferase-eGFP數量：1供應商：BPSBioscienceInc
- 保存條件：
-80°C (dry ice)
- 保質期：
3-18 month
- 英文名：
AAV9 Luciferase-eGFP
- 數量：
1
- 供應商：
BPS Bioscience Inc.
- CAS號：
/
- 規格：
50 µl x 2
Adeno-Associated Virus serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscle, liver, pancreas, and eye tissue. AAV8 and AAV9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making it a desirable candidate for therapeutic applications.These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and eGFP as two separate proteins.
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