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BPS Bioscience Inc.
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當前位置:BPS Bioscience Inc.>>Demethylase Assay Kits>> 50611FBXL11 (KDM2A) Homogeneous Assay Kit

FBXL11 (KDM2A) Homogeneous Assay Kit

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產品型號50611

品       牌BPS Bioscience

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更新時間:2023-11-12 15:12:00瀏覽次數:194次

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●Purchase●DescriptionTheFBXL11HomogeneousAssayKitisdesignedtomeasureFBXL11activityforscreeningandprofilingapplications
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Description

The FBXL11 Homogeneous Assay Kit is designed to measure FBXL11 activity for screening and profiling applications. FBXL11, also known as KDM2A, JHDM1A, and Ndy2, is a histone lysine demethylase that exhibits demethylation activity toward H3-K36Me2.The key to the FBXL11 Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing FBXL11 enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.

50414 scheme 1

Scheme 1: Our histone demethylase assays utilize highly specific antibodies that recognize demethylated products. First, a sample containing the enzyme is incubated with a biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts, as shown above.

Synonyms
Lysine-specific demethylase 2A, KDM2A, JHDM1A, and Ndy2

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