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Complex of human catalytic subunit p110α (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), and human regulatory subunit p85α (phosphoinositide-3-kinase regulatory subunit 1). The two proteins were co-expressed and affinity purified. Recombinant human p110α, encompassing full-length amino acids 2-1068(end). This construct contains an N-terminal Flag-tag and mutation of interest (E545K). Recombinant human p85α, full length encompassing amino acids 1-724(end). This construct does not contain a tag.
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