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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Storage

-20°C/1 year

Specificity

CD2AP Polyclonal Antibody detects endogenous levels of protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from human protein . at AA range: 320-400

Uniprot No

Q9Y5K6

Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

CD2 associated protein(CD2AP) Homo sapiens This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008],

Other

CD2AP, CD2-associated protein (Adapter protein CMS) (Cas ligａnd with multiple SH3 domains)

Concentration

1 mg/ml