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Source

Rabbit

Applications

WB,IHC,ELISA

Reactivity

Human

Dilution

IHC: 100-300.WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Arginase I Polyclonal Antibody detects endogenous levels of Arginase I protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human ARG1. AA range:61-110

Uniprot No

P05089

Alternative names

ARG1; Arginase-1; Liver-type arginase; Type I arginase

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

arginase 1(ARG1) Homo sapiens Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Other

ARG1, Arginase-1

Mol.Wt (Da)

34735

Concentration

1 mg/ml