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Source

Rabbit

Applications

WB,IHC,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CD1D Polyclonal Antibody detects endogenous levels of CD1D protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from Antigen-presenting glycoprotein CD1d at AA range: 161-210

Uniprot No

P15813

Alternative names

CD1D; Antigen-presenting glycoprotein CD1d; R3G1; CD1d

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

CD1d molecule(CD1D) Homo sapiens This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016],

Other

CD1D, Antigen-presenting glycoprotein CD1d

Mol.Wt (Da)

37717

Concentration

1 mg/ml