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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CD141 Polyclonal Antibody detects endogenous levels of CD141 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575

Uniprot No

P07204

Alternative names

THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

thrombomodulin(THBD) Homo sapiens The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],

Other

THBD, Thrombomodulin

Mol.Wt (Da)

60329

Concentration

1 mg/ml