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Source

Rabbit

Applications

WB,IF,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CB2 Polyclonal Antibody detects endogenous levels of CB2 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human CNR2. AA range:191-240

Uniprot No

P34972

Alternative names

CNR2; Cannabinoid receptor 2; CB-2; CB2; hCB2; CX5

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

cannabinoid receptor 2(CNR2) Homo sapiens The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008],

Other

CNR2, Cannabinoid receptor 2

Mol.Wt (Da)

39681

Concentration

1 mg/ml