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Source

Rabbit

Applications

IHC

Reactivity

Human,Rat,Mouse

Dilution

IHC 1:50-100

Storage

-20°C/1 year

Specificity

Cav2.2 protein(A205) detects endogenous levels of Cav2.2

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

Immunogen

Synthetic Peptide of Cav2.2

Uniprot No

Q00975

Alternative names

Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III) (BIII) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Voltage-gated calcium channel subunit alpha Cav2.2)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

calcium voltage-gated channel subunit alpha1 B(CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

Other

CACNA1B, Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III) (BIII) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Voltage-gated calcium channel subunit alpha Cav2.2)

Concentration

1 mg/ml