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Source

Rabbit

Applications

WB,IHC,ELISA

Reactivity

Human,Mouse

Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Cathepsin D Polyclonal Antibody detects endogenous levels of Cathepsin D protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from the Internal region of human Cathepsin D.

Uniprot No

P07339

Alternative names

CTSD; CPSD; Cathepsin D

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

cathepsin D(CTSD) Homo sapiens This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],

Other

CTSD, Cathepsin D

Mol.Wt (Da)

44552

Concentration

1 mg/ml