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Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human

Dilution

WB 1:500-2000, IF 1:50-300, IHC 1:50-300

Storage

-20°C/1 year

Specificity

Caspase-7 Polyclonal Antibody detects endogenous levels of Caspase-7 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from Caspase-7 . at AA range: 160-240

Uniprot No

P55210

Alternative names

CASP7; MCH3; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

caspase 7(CASP7) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

Other

CASP7, Caspase-7

Mol.Wt (Da)

34277

Concentration

1 mg/ml