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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Storage

-20°C/1 year

Specificity

Casein Kinase Iα Polyclonal Antibody detects endogenous levels of Casein Kinase Iα

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CSNK1A1. AA range:161-210

Uniprot No

P48729

Alternative names

Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex.,

Other

CSNK1A1, Casein Kinase Iα

Mol.Wt (Da)

38915

Concentration

1 mg/ml