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Source

Rabbit

Applications

IHC,IF,ELISA

Reactivity

Human,Mouse

Dilution

IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CARD 14 Polyclonal Antibody detects endogenous levels of CARD 14 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human CAR14. AA range:291-340

Uniprot No

Q9BXL6

Alternative names

CARD14; CARMA2; Caspase recruitment domain-containing protein 14; CARD-containing MAGUK protein 2; Carma 2

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

caspase recruitment domain family member 14(CARD14) Homo sapiens This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],

Other

CARD14, Caspase recruitment domain-containing protein 14

Mol.Wt (Da)

113300

Concentration

1 mg/ml