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Source

Rabbit

Applications

IHC,ELISA

Reactivity

Human

Dilution

IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Calcitonin Polyclonal Antibody detects endogenous levels of Calcitonin protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human Calcitonin. AA range:29-78

Uniprot No

P06881/P01258

Alternative names

CALCA; CALC1; Calcitonin gene-related peptide 1; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I; CALCA; CALC1; Calcitonin

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

CALCA (calcitonin related polypeptide alpha) encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for CALCA.

Other

CALCA, Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; CGRP-I; CALCA; CALC1; Calcitonin

Mol.Wt (Da)

13899

Concentration

1 mg/ml