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Source

Rabbit

Applications

IF,ELISA

Reactivity

Human,Mouse,Rat

Dilution

IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Cadherin-23 Polyclonal Antibody detects endogenous levels of Cadherin-23 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110

Uniprot No

Q9H251

Alternative names

CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

cadherin related 23(CDH23) Homo sapiens This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013],

Other

CDH23, Cadherin-23

Mol.Wt (Da)

369525

Concentration

1 mg/ml