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Source

Rabbit

Applications

WB,IHC,ELISA

Reactivity

Human,Mouse

Dilution

WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

ADAMTS-18 Polyclonal Antibody detects endogenous levels of ADAMTS-18 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from ADAMTS-18 . at AA range: 1030-1110

Uniprot No

Q8TE60

Alternative names

ADAMTS18; ADAMTS21; A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

ADAM metallopeptidase with thrombospondin type 1 motif 18(ADAMTS18) Homo sapiens This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016],

Other

ADAMTS18, A disintegrin and metalloproteinase with thrombospondin motifs 18

Mol.Wt (Da)

135141

Concentration

1 mg/ml