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Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

14-3-3 γ Polyclonal Antibody detects endogenous levels of 14-3-3 γ protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human 14-3-3 gamma. AA range:51-100

Uniprot No

P61981

Alternative names

YWHAG; 14-3-3 protein gamma; Protein kinase C inhibitor protein 1; KCIP-1

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma(YWHAG) Homo sapiens This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008],

Other

YWHAG, 14-3-3 protein gamma; Protein kinase C inhibitor protein 1;

Mol.Wt (Da)

28303

Concentration

1 mg/ml