聯系電話
北京祥生興業科技有限公司
中級會員·7年您現在的位置： 北京祥生興業科技有限公司>> 55000-57000非衍生化新生兒篩查遺傳代謝疾病研究質譜分析試劑盒
具體成交價以合同協議為準
- 聯系人：
- 張先生
- 電話：
- 13681184382
- 手機：
- 13681184382
- 地址：
- 北京市北京經濟技術開發區同濟中路甲7號18幢A座1010
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產品簡介
| 供貨周期 | 一個月 | 應用領域 | 醫療衛生,制藥 |
|---|
產品介紹
溫馨提示：僅用于科研，不可用于臨床治療
供應商：
Chromsystems 祥生興業
檢測方法：
串聯質譜分析方法LC-MS/MS
規格：
1set
55000 MassChrom® Amino Acids and Acylcarnitines, Reagent kit for LC-MS/MS analysis
Dried blood spot controls included
Multiple diagnoses in a single run
High selectivity and sensitivity by MS/MS detection
New! Succinylacetone Upgrade Set
57000 MassChrom® Amino Acids and Acylcarnitines/Non Derivatised, Reagent kit for LC-MS/MS analysis
All required and isotope labelled standards included
Dried blood spot controls included
Direct sample injection without derivatisation
High selectivity and sensitivity by MS/MS detection
The Chromsystems reagent kit for the determination of amino acids and acylcarnitines from dried blood spot samples using tandem mass spectrometry is intended for the early diagnosis of amino acid and fatty acid metabolic disorders during newborn screening.
In Germany, newborn screening is regulated by law. Twelve diseases are defined, eight of them to be determined by tandem mass spectrometry. As therapies for only these specific diseases are known, the diagnosis of other diseases is prohibited. Included in these diseases are defects of amino acid metabolism (phenylketonuria and maple syrup urine disease), defects of fatty acid metabolism (Medium and Very Long Chain Acyl-CoA Dehydrogenase Deficiencies) and organoacidurias (isovaleric acidemia). If not detected, these metabolic errors may impair the newborn severely and irreversibly within the first days of its life.
This Chromsystems reagent kit allows the very fast and reliable determination of amino acids and acylcarnitines from dried blood spot samples as part of the newborn screening for amino acid and fatty acid metabolic disorders using tandem mass spectrometry. Sample preparation is based on effective extraction of the analytes from the filter card without any further sample preparation steps required. The test utilises stable isotope labelled internal standards for calibration and measurement to ensure reliable and precise quantification of the analytes. Due to the time saving sample preparation and high precision of the MRM method, this direct injection kit stands out from the derivatised method. On the other hａnd lower sensitivity and interferences from isobaric substances (e.g. C5DC and C6OH) in acylcarnitines analyses may occur.
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